C5b-9 does not mediate tubulointerstitial injury in experimental acute glomerular disease characterized by selective proteinuria

Figure 1 The tubulointerstitial deposition of C5b-9 is increased in C6⁺ rats with protein-overload nephropathy. Representative sections are shown. A: Animal injected with saline (control); B: C6⁺ animal with PON on day 4; C: C6⁺ animal with PON on day 8; D: C6- animal with PON on day 8 (× 400 magnification). Predominant basolateral deposition of C5b-9 was present in PON. PON: Protein-overload nephropathy.