C5b-9 does not mediate tubulointerstitial injury in experimental acute glomerular disease characterized by selective proteinuria

Table 1 Biochemical data in the experimental groups

Group	n	Serum protein (g/dL)	Serum albumin (g/dL)	Proteinuria (mg/24 h)	Serum creatinine (mmol/L)	Serum urea (mmol/L)
Control	9	65 ± 1	39 ± 1	2 ± 1	43 ± 3	7 ± 0
		(65, 63-66)	(39, 37-42)	(2, 1-2)	(40, 36-48)	(7, 6-8)
PON d 2 C6+	6	98 ± 31	74 ± 11	857 ± 1761	97 ± 171	27 ± 51
		(97, 92-102)	(74, 73-76)	(972, 679-1080)	(86, 67-117)	(23, 17-38)
PON d 2 C6-	5	97 ± 51	74 ± 41	789 ± 2141	117 ± 311	35 ± 111
		(99, 93-104)	(76, 71-79)	(788, 11-1145)	(97, 64-177)	(21, 17-58)
PON d 4 C6+	6	101 ± 21	73 ± 11	1214 ± 1311	93 ± 91	24 ± 21
		(102, 97-109)	(75, 72-76)	(1094, 1013-1197)	(94, 80-125)	(25, 20-30)
PON d 4 C6-	6	96 ± 21	70 ± 11	1026 ± 2671	76 ± 51	19 ± 11
		(95, 89-98)	(69, 67-73)	(965, 724-1719)	(73, 65-85)	(18, 17-21)
PON d 8 C6+	8	97 ± 31	68 ± 31	1177 ± 701	74 ± 61	24 ± 31
		(97, 88-101)	(70, 64-72)	(1165, 709-1321)	(65, 53-81)	(20, 15-29)
PON d 8 C6-	9	97 ± 21	70 ± 31	1227 ± 1161	69 ± 61	22 ± 31
		(99, 95-101)	(71, 70-73)	(1228, 952-1529)	(73, 52-86)	(19, 17-28)

Data are expressed as mean ± SEM (median, Inter-quartile range);

¹P < 0.05 compared to control group. PON: Protein-overload nephropathy.