Matrix metalloproteinase-2 as a superior biomarker for peritoneal deterioration in peritoneal dialysis

Table 3 Correlation between patient characteristics and effluent biomarker levels

	Biomarker levels in the peritoneal effluents
	MMP-2	IL-6	Hyaluronan	CA125
Sex (male/female)	P = 0.92	P = 0.54	P = 0.48	P < 0.05
Etiology (non-DM/DM)	P = 0.18	P = 1.00	P = 0.56	P < 0.05
Age (yr)	ρ = 0.076	ρ = 0.12	ρ = 0.046	ρ = -0.096
	P = 0.27	P = 0.092	P = 0.50	P = 0.16
PD duration (mo)	ρ = 0.050	ρ = 0.15	ρ = 0.25	ρ = -0.062
	P = 0.47	P < 0.05	P < 0.01	P = 0.93
Peritonitis episode (times)	ρ = 0.17	ρ = 0.25	ρ = 0.092	ρ = -0.012
	P < 0.05	P < 0.001	P = 0.20	P = 0.86

ρ values were derived from Spearman’s correlation coefficient. PD: Peritoneal dialysis; MMP-2: Matrix metalloproteinase-2; IL-6: Interleukin-6; CA125: Cancer antigen 125; DM: Diabetes mellitus; non-DM: Non-diabetes mellitus.