Complement involvement in kidney diseases: From physiopathology to therapeutical targeting

doi:10.5527/wjn.v4.i2.169

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World Journal of Nephrology

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2220-6124

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Nephrol. May 6, 2015; 4(2): 169-184
Published online May 6, 2015. doi: 10.5527/wjn.v4.i2.169

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Figure 4 Significance of inhibiting the C5-C5a receptor axis. C5 convertases formed during activation of complement cascade cleave C5 into its active products. Inhibition is feasible pharmacologically or with neutralizing antibodies. MAC: Membrane attack complex; STAT3: Signal transducers and activators of transcription 3.

Citation: Salvadori M, Rosso G, Bertoni E. Complement involvement in kidney diseases: From physiopathology to therapeutical targeting. World J Nephrol 2015; 4(2): 169-184
URL: https://www.wjgnet.com/2220-6124/full/v4/i2/169.htm
DOI: https://dx.doi.org/10.5527/wjn.v4.i2.169