African origins and chronic kidney disease susceptibility in the human immunodeficiency virus era

Table 1 Spectrum of renal histology in human immunodeficiency virus in South Africa

Histology	Durban[21]	JHB[20]	Cape Town[22]	JHB1
Biopsy numbers	30	99	192	364
Classic HIVAN (%)	83	27	24.4	32.7
FSGS		3	32.8	11.3
HIV Immune Complex Disease (%) (mostly with hepatitis B or C co-infection)		21	30.2	11.8
Mesangial proliferative		6
Membranoproliferative (type I and III) (%)	7			2.7
Lupus-like (%)				4.4
IgA
Membranous (%)	13.3	13	5.2	7.7
Exudative-proliferative
HIV TTP/HUS (thrombotic microangiopathy)
Various glomerulonephropathies (%) (heterogenous group with different aetiologies)	7	41	24	29.4
Minimal change (%)		2		3.3
Immunotactoid
Amyloidosis

¹Adapted from Vermeulen Alda, MMed Research report, University of the Witwatersrand, 2014[83]. JHB: Johannesburg; HIVAN: Human immunodeficiency virus-associated nephropathy; TTP: Thrombotic thrombocytopaenic purpura; HUS: Haemolytic syndrome.