Lipid abnormalities in kidney disease and management strategies

Table 4 Kidney disease: Developing global guidelines recommendations for dyslipidemia treatment among chronic kidney disease groups

CKD groups	KDIGO recommendations for dyslipidemia
CKD patients not on dialysis	In adults ≥ 50 yr with eGFR ≥ 60 mL/min per 1.73 m2, treatment with statins is recommended
	In adults ≥ 50 yr with eGFR ≤ 60 mL/min per 1.73 m2, treatment with statins or statins/ezetimibe combination is recommended
	In adults 18-49 yr, treatment with statins is recommended if they have one or more of the following risk factors:
	Known coronary disease
	Diabetes mellitus
	Prior ischemic stroke
	Estimated 10-yr incidence of coronary death or non-fatal myocardial infarction > 10%
CKD patients ON dialysis	In adult CKD patients on dialysis, initiation of statin or statin/ezetimibe combination is not recommended
	In adult dialysis patients who are already on statin or statin/ezetimibe combination at the initiation of dialysis, these agents should be continued
Kidney transplant patients	In adult patients with kidney transplant, treatment with statin is recommended

Adapted from Tonelli et al[45]. CKD: Chronic kidney disease; eGFR: Estimated glomerular filtration rate.