Role of endoscopic ultrasound fine-needle aspiration evaluating adrenal gland enlargement or mass

Table 7 Comparison of different Studies evaluating adrenal gland endoscopic ultrasound guided fine-needle aspiration

Ref.	Year	Number of patients	Patient population	EUS-FNA Left adrenal, n	Patient population	EUS-FNA Left adrenal, n	EUS-FNA Right adrenal, n	Benign EUS-FNA cytology, n	Malignant EUS-FNA cytology (n)	Non-Diagnostic rate	Sensitivity	Specificity	PPV	NPV	F/U for benign lesions	Method for F/U
Current research	2014	94	Patients undergoing EUS-FNA of either adrenal	94	Patients undergoing EUS-FNA of either adrenal	90	5	60	25	10%	86%	97%	96%	89%	Available on 36/60	CT/MRI, repeat EUS at ≥ 6 mo or surgical pathology from adrenalectomy
1Uemura et al[13]	2013	150	Potentially resectable lung cancer	150	Potentially resectable lung cancer	91	51	7	4	0%	100%	100%	100%	100%	Available in 4/7	F/U CT at 6 months
Schuurbiers et al[17]	2011	85	Lung cancer	150	Lung cancer	85	0	25	55	6%	86%	96%	91%	70%	Available in 23/30	Clinical (n = 11) or F/U CT (n = 10)2
Eloubeidi et al[12]	2010	59	Known or suspected malignancy	59	Known or suspected malignancy	54	5	37	22	0%	NR	NR	NR	NR	Clinical F/U for 37	Not part of study protocol
Bodtger et al[4]	2009	40	Known or suspected lung cancer	40	Known or suspected lung cancer	40	0	29	11	0%	94%	43%	91%	55%	Available	Survival at 2 yr

¹EUS-FNA was done in 11 patients, 3 had bilateral EUS-FNA;

²Two patients had CT at 3 mo. EUS-FNA: Endoscopic ultrasound guided fine-needle aspiration; PPV: Positive predictive value; NPV: Negative predictive value; FNA: Fine-needle aspiration; F/U: Follow up; N/A: Not available; NR: Not reported; CT: Computerized Tomography.