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World J Nephrol. Aug 6, 2014; 3(3): 107-113
Published online Aug 6, 2014. doi: 10.5527/wjn.v3.i3.107
Published online Aug 6, 2014. doi: 10.5527/wjn.v3.i3.107
Table 2 Tacrolimus dose, trough level and kidney function in the two groups
1 wk | 1 mo | 2 mo | 1 yr | 3 yr | 5 yr | |
Tacrolimus dose (mg/d) | ||||||
Group 1 | 10.9 ± 5.6 | 7.5 ± 4.8 | 6.0 ± 3.6 | 5.6 ± 3.8 | 5.3 ± 3.1 | 4.9 ± 2.8 |
Group 2 | 8.6 ± 4.1 | 8.3 ± 3.7 | 8.1 ± 3.2 | 7.8 ± 3.0 | 7.0 ± 2.2 | 6.2 ± 2.5 |
P value | 0.004 | 0.03 | < 0.001 | < 0.001 | < 0.001 | < 0.001 |
Tacrolimus trough level (× 10 mg/L) | ||||||
Group 1 | 11.3 ± 2.1 | 9.7 ± 1.9 | 9.3 ± 1.7 | 8.6 ± 2.1 | 6.4 ± 1.9 | 5.3 ± 1.4 |
Group 2 | 10.7 ± 1.8 | 10.2 ± 2.0 | 9.5 ± 1.6 | 9.0 ± 1.8 | 5.8 ± 1.7 | 4.8 ± 1.5 |
Serum Cr (× 10 mg/L) | ||||||
Group 1 | 2.2 ± 1.3 | 1.7 ± 1.1 | 1.5 ± 0.9 | 1.6 ± 1.2 | 1.6 ± 0.8 | 1.7 ± 0.9 |
Group 2 | 1.9 ± 1.1 | 1.7 ± 0.9 | 1.6 ± 0.7 | 1.5 ± 0.8 | 1.5 ± 0.7 | 1.6 ± 0.8 |
- Citation: Khan E, Killackey M, Kumbala D, LaGuardia H, Liu YJ, Qin HZ, Alper B, Paramesh A, Buell J, Zhang R. Long-term outcome of ketoconazole and tacrolimus co-administration in kidney transplant patients. World J Nephrol 2014; 3(3): 107-113
- URL: https://www.wjgnet.com/2220-6124/full/v3/i3/107.htm
- DOI: https://dx.doi.org/10.5527/wjn.v3.i3.107