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©2014 Baishideng Publishing Group Co.
World J Nephrol. Feb 6, 2014; 3(1): 6-15
Published online Feb 6, 2014. doi: 10.5527/wjn.v3.i1.6
Published online Feb 6, 2014. doi: 10.5527/wjn.v3.i1.6
Table 6 Univariate Cox proportional hazard analysis of renal end point, according to clinical variables
HR | 95%CI | P value | ||
Lower | Upper | |||
Age (yr) | 1.00 | 0.97 | 1.03 | |
Sex (men) | 1.19 | 0.50 | 2.85 | |
Diabetes type (2/1) | 0.76 | 0.31 | 1.91 | |
Diabetes duration (years) | 1.01 | 0.95 | 1.07 | |
BMI < 30 (yes/no) | 2.94 | 1.09 | 7.69 | 0.03 |
Smoker (yes/no) | 0.92 | 0.34 | 2.50 | |
Hypertension (yes/no) | 1.01 | 0.13 | 7.69 | |
CVD (yes/no) | 4.56 | 1.94 | 10.69 | 0.000 |
Retinopathy (yes/no) | 1.24 | 0.56 | 2.75 | |
Baseline Serum creatinine (mg/dL) | 2.18 | 1.14 | 4.16 | 0.02 |
Baseline eGFR (mL/min per 1.73 m2) | 0.98 | 0.95 | 1.00 | |
1Baseline proteinuria (g/g) | 1.12 | 0.98 | 1.27 | |
eGFR drop > 25% before biopsy | 3.96 | 1.54 | 10.18 | 0.004 |
Serum creatinine (mg/dL) at biopsy | 2.97 | 1.91 | 4.61 | 0.000 |
eGFR (mL/min per 1.73 m2) at biopsy | 0.94 | 0.92 | 0.97 | 0.000 |
RPKI | 2.74 | 1.21 | 6.24 | 0.02 |
2Proteinuria at biopsy (g/d) | 1.09 | 0.97 | 1.23 | |
Hematuria | 1.65 | 0.72 | 3.82 | |
Serum albumin (g/dL) | 0.75 | 0.41 | 1.35 | |
HbA1c % (< 7/≥ 7) | 3.37 | 1.23 | 9.25 | 0.02 |
Total cholesterol (mg/dL) | 0.98 | 0.96 | 1.01 | |
RAASI treatment (yes/no) | 0.59 | 0.22 | 1.59 | |
Statin treatment | 0.66 | 0.27 | 1.62 | |
Silent DN | 3.04 | 1.26 | 7.3 | 0.02 |
- Citation: López-Revuelta K, Galdo PP, Stanescu R, Parejo L, Guerrero C, Pérez-Fernández E. Silent diabetic nephropathy. World J Nephrol 2014; 3(1): 6-15
- URL: https://www.wjgnet.com/2220-6124/full/v3/i1/6.htm
- DOI: https://dx.doi.org/10.5527/wjn.v3.i1.6