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©2013 Baishideng Publishing Group Co.
World J Nephrol. Aug 6, 2013; 2(3): 56-76
Published online Aug 6, 2013. doi: 10.5527/wjn.v2.i3.56
Published online Aug 6, 2013. doi: 10.5527/wjn.v2.i3.56
Table 3 Gene mutation rate of different complement factors according r-hemolytic uremic syndrome registries data
| Abnormality | Gene locus | Atypical HUS rate |
| Factor H | CFH (RCA:1q32) | 11%-29% |
| Membrane co-factor protein | MCP (RCA) | 3%-17% |
| Factor I | CFI (4q25) | 2%-17% |
| C3 | C3 (19p13) | 2%-17% |
| Factor B | CFB (6p21) | 0%-5% |
| Thrombomodulin | THBD (20p11) | 0%-5% |
| Anti factor H autoantibodies | 4%-13% |
- Citation: Salvadori M, Bertoni E. Update on hemolytic uremic syndrome: Diagnostic and therapeutic recommendations. World J Nephrol 2013; 2(3): 56-76
- URL: https://www.wjgnet.com/2220-6124/full/v2/i3/56.htm
- DOI: https://dx.doi.org/10.5527/wjn.v2.i3.56