Pericytes synthesize renin

Figure 3 Quantification and comparison of pericytes positive for renin in wild type and angiotensinogen deficient mice. A: In wild type (WT) mice the density of renin positive pericytes was not significantly different from E18 to P21, but significantly decreased at P45 (P = 0.0052 vs E18) and P70 (P = 0.0007 vs E18); B: Angiotensinogen deficient (AGT) -/- mice showed a significant increase at P5 with a maximum at P10 and a progressive decrease towards P70 (^bP≤ 0.01 vs E18); C: Comparison at each individual age showing a significant increase in the number of renin-positive pericytes in AGT -/- from P5 till P70 (^dP≤ 0.001 vs WT).