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©2013 Baishideng.
Figure 2 Nephrin-adaptors complex.
Adaptor proteins including CD2-associated protein (CD2AP) and Nck, anchor nephrin and podocin to the cytoskeleton, maintain podocyte cytoskeletal structure and modulate the signaling pathway between the slit diaphragm and cytoskeleton. PI3-K: Phosphoinositide 3-kinase; N-WASP: Neuronal Wiskott-Aldrich syndrome protein.
- Citation: Ha TS. Roles of adaptor proteins in podocyte biology. World J Nephrol 2013; 2(1): 1-10
- URL: https://www.wjgnet.com/2220-6124/full/v2/i1/1.htm
- DOI: https://dx.doi.org/10.5527/wjn.v2.i1.1