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©The Author(s) 2025.
World J Nephrol. Jun 25, 2025; 14(2): 103035
Published online Jun 25, 2025. doi: 10.5527/wjn.v14.i2.103035
Published online Jun 25, 2025. doi: 10.5527/wjn.v14.i2.103035
Table 6 Summary of key clinical differences among emphysematous pyelonephritis groups
| Clinical parameter | Group 1 (NEWS 2: 0-6, n = 83) | Group 2 (NEWS 2: 7-14, n = 76) | Group 3 (NEWS 2: 15-20, n = 12) | P value |
| Percentage (95%CI)/mean ± SD (95%CI) | ||||
| Age > 50 years (%) | 67.50 (58.9-75.4) | 75 (65.4-82.8) | 100 (73.5-100) | 0.046 |
| Body temperature extremes (%) | 0 (0-4.4) | 9.21 (4.5-17.8) | 58.30 (34.8-78.4) | < 0.01 |
| Shock at presentation (%) | 1.20 (0.2-6.5) | 26.30 (18.2-36.1) | 91.70 (65.3-98.8) | < 0.01 |
| Altered consciousness (%) | 1.20 (0.2-6.5) | 32.90 (24.2-42.9) | 66.70 (41.0-85.6) | < 0.01 |
| Palpable tender kidney (%) | 8.40 (4.1-16.3) | 63.20 (52.4-72.9) | 100 (73.5-100) | < 0.01 |
| Presence of diabetes mellitus (%) | 85.6 (76.1-92) | 96.1 (88.9-99.18) | 100 (73.5-100) | 0.035 |
| Need for intensive care unit care (%) | 10.80 (6.0-18.6) | 56.60% (45.7-66.9) | 100 (73.5-100) | < 0.01 |
| Need for hemodialysis (%) | 6.00 (2.7-12.7) | 19.70% (12.7-29.2) | 91.70 (65.3-98.8) | < 0.01 |
| Early nephrectomy (%) | 0 (0-4.4) | 2.60 (0.7-9.0) | 50 (26.9-73.1) | < 0.01 |
| Mortality (%) | 0 (0-4.4) | 1.30 (0.2-6.9) | 58.30 (34.8-78.4) | < 0.01 |
| Heart rate (per minute) | 86.71 ± 12.58 (84.004- 89.416) | 90.03 ± 17.79 (86.03-94.03) | 110.75 ± 21.16 (98.78-122.72) | < 0.01 |
| Mean blood sugar (mg/dL) | 245.6 ± 100.8 (225.4-265.8) | 323.2 ± 129.3 (298.5-347.9) | 346.2 ± 59.1 (325.4-367.0) | < 0.01 |
| Serum creatinine (mg/dL) | 3.18 ± 2.21 (2.7-3.6) | 3.92 ± 2.54 (3.3-4.5) | 5.14 ± 1.45 (4.6-5.7) | 0.003 |
| Serum albumin (g/dL) | 3.14 ± 0.65 (2.9-3.3) | 3.08 ± 0.73 (2.9-3.3) | 2.39 ± 0.45 (2.2-2.6) | 0.004 |
| Hemoglobin A1c | 8.712 ± 2.55 (8.16- 9.26) | 9.375 ± 1.7 (8.99-9.76) | 10.07 ± 2.59 (8.665-11.53) | 0.023 |
| Sodium (mEq/L) | 131.94 ± 6.03 (130.3-133.6) | 131.90 ± 5.76 (130.3-133.4) | 123.58 ± 4.89 (121.4-125.8) | < 0.01 |
| International normalized ratio test | 1.18 ± 0.18 (1.14- 1.22) | 1.27 ± 0.31 (1.2- 1.34) | 1.86 ± 0.61 (1.515-2.205) | < 0.01 |
| Platelet count | 220695 ± 128292 (189345-252045) | 124053 ± 87178 (101345-146761) | 54575 ± 25853 (45676-63474) | < 0.01 |
| Computed tomography class 3/4 (%) | 20.50 (13.6-29.6) | 30.30 (21.5-40.4) | 100% (73.5-100) | < 0.01 |
| Risk stratification index (mean ± SD) | 1.867 ± 0.35 (1.8-2.0) | 2.039 ± 0.45 (1.9-2.2) | 3.75 ± 0.50 (3.5-4.0) | < 0.01 |
| Combined prognostic scoring index (mean ± SD) | 10.74 ± 3.81 (9.8-11.7) | 12.95 ± 3.90 (11.9-14.0) | 21.92 ± 2.61 (20.9-23.0) | < 0.01 |
- Citation: Krishnamoorthy S, Thiruvengadam G, Sekar H, Palaniyandi V, Ramadurai S, Narayanasamy S. Modified National Early Warning Score 2, a reliable early warning system for predicting treatment outcomes in patients with emphysematous pyelonephritis. World J Nephrol 2025; 14(2): 103035
- URL: https://www.wjgnet.com/2220-6124/full/v14/i2/103035.htm
- DOI: https://dx.doi.org/10.5527/wjn.v14.i2.103035