Investigating the controversial link between pediatric obesity and graft survival in kidney transplantation

doi:10.5527/wjn.v14.i2.101961

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Jun 25, 2025 (publication date) through Apr 21, 2025

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World Journal of Nephrology

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2220-6124

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

World J Nephrol. Jun 25, 2025; 14(2): 101961
Published online Jun 25, 2025. doi: 10.5527/wjn.v14.i2.101961

Table 3 Median graft survival and median patient survival between the different body mass index categories

	Underweight (< 5^th)	Healthy weight (5^th-85^th)	Overweight (85^th-95^th)	Class 1 obese (95^th-120%95^th)	Class 2 obese (120%-140%95^th)	Class 3 obese (> 140%95^th)
Median graft survival (95%CI) (years)	11.6 (10.9-12.3)^b^,^c^,^d^,^e^,^f	12.2 (11.9–12.4)^a^,^e	11.9 (11.4–12.4)^a^,^e	12.0 (11.4–12.6)^a^,^e	9.7 (8.7–10.6)^a^,^e	11.8 (10.5–13.0)^a^,^b^,^c^,^d^,^e
1-year graft survival rate	92.2%^f	93.1%^f	92.6%^f	92.0%^f	92.7%^f	88.7%^a^,^b^,^c^,^d^,^e
5-year graft survival rate	71.3%^b^,^c^,^d	73.8%^a^,^e^,^f	73.1%^a^,^e^,^f	73.6%^a^,^e^,^f	67.8%^b^,^c^,^d	68.3%^b^,^c^,^d
10-year graft survival rate	45.0%^b^,^c^,^d^,^f	46.8%^a^,^e	47.0%^a^,^e	49.5%^a^,^e	40.7%^b^,^c^,^d^,^f	48.7%^a^,^e
Median patient survival (95%CI) (years)	26.9 (24.4-29.4)^f	26.0 (24.7-27.2)^f	24.8 (23.6–25.9)^f	24.8 (22.9-26.7)^f		23.1 (21.1-25.0)^a^,^b^,^c^,^d
1-year graft survival rate	92.2%	93.1%	92.6%	92.0%	92.7%	88.7%
5-year patient survival rate	93.6%^c^,^d	92.5%^c^,^d	95.6%^a^,^b^,^e^,^f	94.6%^a^,^b^,^e^,^f	92.6%^c^,^d	91.3%^c^,^d
10-year patient survival rate	81.3%^b^,^c^,^d	85.5%^a^,^e^,^f	86.7%^a^,^e^,^f	86.1%^a^,^e^,^f	78.9%^b^,^c^,^d	79.9%^b^,^c^,^d

^aP < 0.05 vs underweight.

^bP < 0.05 vs healthy weight.

^cP < 0.05 vs overweight.

^dP < 0.05 vs obese I.

^eP < 0.05 vs obese II.

^fP < 0.05 vs obese III.

Citation: Stanicki B, Puntiel DA, Peticca B, Egan N, Prudencio TM, Robinson SG, Karhadkar SS. Investigating the controversial link between pediatric obesity and graft survival in kidney transplantation. World J Nephrol 2025; 14(2): 101961
URL: https://www.wjgnet.com/2220-6124/full/v14/i2/101961.htm
DOI: https://dx.doi.org/10.5527/wjn.v14.i2.101961