Glomerular filtration rate and comorbidity factors in elderly hospitalizations

Table 1 Patients characteristics, mean ± SD

Variable	G1	G2	G3a	G3b	G4	G5	P value
Age of males, years	81.7 ± 5.8	80.6 ± 3.9	81.7 ± 5.8	80.6 ± 3.9	82.6 ± 5.0	82.5 ± 4.7	0.106
Age of females, years	79.9 ± 3.5	80.1 ± 3.9	79.9 ± 3.5	80.1 ± 3.9	81.8 ± 4.8	81.8 ± 3.9
Serum urea nitrogen (mg/dL)	19 ± 8	21 ± 7	28 ± 13	39 ± 20	63 ± 28	87 ± 25	0.01
Creatinine (mg/dL)	0.64 ± 0.1	0.87 ± 0.1	1.18 ± 0.17	1.56 ± 0.2	2.42 ± 0.55	4.88 ± 2.09	0.01
GFR (mL/kg/1.73 m2)	109.1 ± 18	72.4 ± 8.1	52.2 ± 4.2	37.8 ± 4.6	23.1 ± 4.4	11.1 ± 3.2	0.01
Hemoglobin (g/dL)	11 ± 3	11 ± 3	11 ± 3	11 ± 2	11 ± 2	11 ± 2	0.01
Hematocrit (g/dL)	33 ± 9	35 ± 8	34 ± 9	33 ± 7	34 ± 8	34 ± 7	0.01
No comorbidity, n (%)	111 ± 24, 24 (16.3)	73.7 ± 9, 64 (43.5)	52.5 ± 4.6, 29 (19.7)	38.8 ± 4.1, 21 (14.3)	23.4 ± 3.3, 7 (4.8)	12.5 ± 2.1, 2 (1.4)	0.010
MDS, n (%)	136 ± 36, 4 (16)	69 ± 6.7, 12 (48)	48.1 ± 3.4, 3 (12)	35.4 ± 4.1, 4 (16)	20.7 ± 6, 12 (8)	0	0.396
Diabetes, n (%)	105 ± 11.5, 21 (12.7)	72.6 ± 7.7, 43 (25.9)	51.8 ± 3.6, 27 (16.3)	37.5 ± 4.6, 42 (25.3)	23.2 ± 4.4, 18 (10.8%)	11 ± 3.4, 15 (9%)	0.020
Alzheimer’s, n (%)	112 ± 12, 11 (25)	74.6 ± 7.8, 9 (20.5)	50.5 ± 3.3, 6 (13.6)	35.7 ± 5, 6 (13.6)	24.9 ± 3.8, 9 (20.5%)	8.1 ± 4, 3 (6.8%)	0.078
CAD, n (%)	103 ± 0.6, 2 (9.5)	70.5 ± 10, 552.2 ± 8 (31)	52.2 ± 5.5, 2 (9.5)	35.3 ± 3, 3 (14.3)	24.5 ± 6.7, 3 (14.3)	11.5 ± 1.3, 3 (14.3)	0.690
CVO, n (%)	95.8 ± 6.4, 2 (20)	69.6, 1 (10)	0	36.6 ± 8.9, 2 (20)	16.9, 1 (10)	12 ± 2.8, 4 (40)	0.046
Arterial hypertension, n (%)	107 ± 15, 27 (16)	71 ± 7.4, 57 (33.9)	52.6 ± 4.5, 24 (14.3)	39.1 ± 4.5, 24 (14.3)	22.2 ± 4.5, 19 (11.3)	11.3 ± 3.5, 17 (10.1)	0.341
COPD, n (%)	111.6, 1 (12.5)	74.9 ± 17, 2 (25)	54 ± 2, 43 (37.5)	0	21.9 ± 5.2, 2 (25)	0	0.279
Cancer, n (%)	0	81.4, 1 (9,1)	56.9 ± 2.1, 2 (18.2)	37.2 ± 5.3, 6 (54.5)	28.5, 1 (9.1)	10.2, 1 (9.1)	0.034

GFR: Glomerular filtration rate; MDS: Myelodysplastic syndrome; CAD: Coronary artery disease; CVO: Cerebrovascular disease; COPD: Chronic obstructive pulmonary disease.