Relationship of lupus nephritis and pregnancy: A narrative review

Table 3 Medication compatibility with pregnancy and lactation

Medications	Before conception	During pregnancy	Lactation
Stop at conception
Abatacept	Stop with the positive pregnancy test		+
Belimumab	Stop with the positive pregnancy test		+
Rituximab	Stop with the positive pregnancy test		+
Compatible drugs
Hydroxychloroquine	+	+	+
Azathioprine	+	+	+
Cyclosporine	+	+	+
Tacrolimus	+	+	+
Sulfasalazine	+	+	+
Prednisone	Dose < 20 mg/day	Dose < 20 mg/day	Dose < 20 mg/day
NSAIDs	Discontinue w/difficulty conceiving	Stop at week 20	+
Non-compatible drugs
Cyclophosphamide	Stop 3 months before conception	x	x
MMF/mycophenolic acid	Stop 6 weeks before conception	x	x
Methotrexate	Stop 1-3 months before conception	x	x low transfer into breast milk

NSAIDs: Non-steroidal anti-inflammatory drugs; MMF: Mycophenolate mofetil.