Clinical course and outcome of adult patients with primary focal segmental glomerulosclerosis with kidney function loss on presentation

Figure 2 Histopathological features of focal segmental glomerulosclerosis variants. A: Tip variant showing segmental scarring involving the tip domain of the glomerulus opposite the vascular pole (green arrow) [periodic acid-Schiff (PAS) stain, 400 ×]; B: Collapsing focal segmental glomerulosclerosis showing global collapse of capillary tufts associated with podocyte hypertrophy and hyperplasia [Jones Methenamine silver (JMS) stain, 200 ×]; C: Perihilar variant showing segmental scarring involving the vascular pole of the glomerulus (green arrow) (PAS stain, 400 ×); D: Cellular variant showing the expansion of a segment of glomerulus by endocapillary hypercellularity associated with mild podocyte hyperplasia (green arrow) (JMS stain, 400 ×).