Neutrophil gelatinase-associated lipocalin, kidney injury molecule-1, and periostin: Novel urinary biomarkers in diabetic nephropathy

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Dec 25, 2024 (publication date) through Nov 8, 2024

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World Journal of Nephrology

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2220-6124

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Nephrol. Dec 25, 2024; 13(4): 98880
Published online Dec 25, 2024. doi: 10.5527/wjn.v13.i4.98880

Table 3 Correlation of urinary neutrophil gelatinase-associated lipocalin, kidney injury molecule-1and periostin with other parameters

Parameter	ACR	Neutrophil gelatinase-associated lipocalin	Kidney injury molecule-1	Periostin
Duration of diabetes mellitus	R = 0.457, P ≤ 0.001^b	-	-	-
Creatinine	R = 0.194, P = 0.014^a	R = 0.218, P = 0.006^b	R = 0.270, P = 0.001^b	R = 0.226, P = 0.004^b
Fasting blood sugar	R = 0.182, P = 0.021^a	R = 0.352, P ≤ 0.001^b	R = 0.192, P = 0.015^a	R = 0.376, P ≤ 0.001^b
Postprandial blood sugar	R = 0.248, P = 0.002^b	R = 0.383, P ≤ 0.001^b	R = 0.231, P = 0.003^b	R = 0.449, P ≤ 0.001^b
Glycated hemoglobin	R = 0.225, P = 0.004^b	R = 0.425, P ≤ 0.001^b	R = 0.295, P ≤ 0.001^b	R = 0.406, P ≤ 0.001^b
ACR	-	R = 0.339, P ≤ 0.001^b	R = 0.219, P = 0.005^b	R = 0.302, P ≤ 0.001^b
Estimated glomerular filtration rate	R = -0.292, P ≤ 0.001^b	R = -0.325, P ≤ 0.001^b	R = -0.299, P ≤ 0.001^b	R = -0.275, P ≤ 0.001^b

^aSignifies P < 0.05.

^bSignifies P value < 0.01.

ACR: Albumin creatinine ratio; R: Correlation coefficient.

Citation: Varatharajan S, Jain V, Pyati AK, Neeradi C, Reddy KS, Pallavali JR, Pandiyaraj IP, Gaur A. Neutrophil gelatinase-associated lipocalin, kidney injury molecule-1, and periostin: Novel urinary biomarkers in diabetic nephropathy. World J Nephrol 2024; 13(4): 98880
URL: https://www.wjgnet.com/2220-6124/full/v13/i4/98880.htm
DOI: https://dx.doi.org/10.5527/wjn.v13.i4.98880