Review
Copyright ©The Author(s) 2024.
World J Nephrol. Dec 25, 2024; 13(4): 98709
Published online Dec 25, 2024. doi: 10.5527/wjn.v13.i4.98709
Table 3 Glucocorticoid regimens used in clinical trials of IgAN
Ref.
Medication
Initial dose
Taper
Total exposure
Lv et al[63]Methylprednisolone0.4 mg/kg orally once dailyReduce daily dose by 4 mg every month6 months
Lv et al[64]Methylprednisolone0.6 to 0.8 mg/kg orally once dailyReduce daily dose by 8 mg every month6 months
Manno et al[65]Prednisone1 mg/kg orally per dayReduce daily dose by 0.2 mg/kg every month6 months
Lv et al[66]Prednisone0.8 to 1 mg/kg orally per dayReduce daily dose by 5 to 10 mg every 2 weeks6 months
Pozzi et al[67]MethylprednisoloneMethylprednisolone 1 g IV for 3 days, followed by prednisoloneNone6 months
Rauen et al[68]Prednisolone/prednisonePrednisolone or prednisone 05 mg/kg orally ever other dayNone6 months
Fellström et al[59]TRF- budesonide16 mg orally dailyReduce dose to 8 mg once daily for 2 weeks9 months