Detection of decline in estimated glomerular filtration rate in patients with type 2 diabetes by cystatin C-based equations

Table 6 The agreements between estimated glomerular filtration rate equations

Equations		CKD-EPI 2021 creatinine-cystatin C (mL/min/1.73m2)		Kappa coefficients (P1 value)
		< 60	≥ 60
Cockcroft-Gault (mL/min/1.73 m2)	< 60	19	20	0.43 (P < 0.001)
	≥ 60	4	50
MDRD (mL/min/1.73 m2)	< 60	15	3	0.66 (P < 0.001)
	≥ 60	8	67
CKD-EPI 2021 creatinine (mL/min/1.73 m2)	< 60	9	0	0.49 (P < 0.001)
	≥ 60	14	70
CKD-EPI 2012 cystatin C (mL/min/1.73 m2)	< 60	19	20	0.44 (P < 0.001)
	≥ 60	4	50

¹Kappa statistic.

MDRD: Modification of Diet in Renal Disease; CKD-EPI: Chronic Kidney Disease Epidemiology Collaboration.