Detection of decline in estimated glomerular filtration rate in patients with type 2 diabetes by cystatin C-based equations

Table 5 Estimated glomerular filtration rate values and its correlation with serum cystatin C concentration

eGFR (mL/min/1.73 m2)	Type 2 diabetes		P value	Correlation between eGFR values and Scys
	Yes (n = 47)	No (n = 46)		r	P1 value
Cockcroft-Gault	64.7 ± 22.5	67.3 ± 20.6	0.56	-0.47	< 0.01
MDRD	72 ± 0.19	80 ± 0.17	0.06	-0.59	< 0.01
CKD-EPI 2021 creatinine	102.8 ± 32.8	109.1 ± 30.9	0.34	-0.59	< 0.01
CKD-EPI 2012 cystatin C	55.6 ± 17.1	58.7 ± 15.4	0.35	-0.86	< 0.01
CKD-EPI 2021 creatinine-cystatin C	66.8 ± 14.6	70.4 ± 13.8	0.23	-0.91	< 0.01

¹Pearson’s correlation coefficient.

eGFR: Estimated glomerular filtration rate; MDRD: Modification of Diet in Renal Disease; CKD-EPI: Chronic Kidney Disease Epidemiology Collaboration; Scys: Serum cystatin C.