Detection of decline in estimated glomerular filtration rate in patients with type 2 diabetes by cystatin C-based equations

doi:10.5527/wjn.v13.i4.95761

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World Journal of Nephrology

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2220-6124

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Nephrol. Dec 25, 2024; 13(4): 95761
Published online Dec 25, 2024. doi: 10.5527/wjn.v13.i4.95761

Table 2 Estimated glomerular filtration rate equations

Names	Equations
Cock-Croft Gault (mL/min)	eGFR = [(140-age) × weight]/(72 × Scr) (× 0.85 if female)
MDRD (mL/min/1.73 m²)	eGFR = 186 × (Scr)^-1.154 × (age)^-0.203 × (0.742 if female) × (1.210 if African American)
CKD-EPI 2021 creatinine (mL/min/1.73 m²)	Female	Scr ≤ 0.7	eGFR = 142 × (Scr/0.7)^-0.241 × 0.9938^age × 1.012
	Female	Scr > 0.7	eGFR = 142 × (Scr/0.7)^-1.200 × 0.9938^age × 1.012
	Male	Scr ≤ 0.9	eGFR = 142 × (Scr/0.9)^-0.302 × 0.9938^age
	Male	Scr > 0.9	eGFR = 142 × (Scr/0.9)^-1.200 × 0.9938^age
CKD-EPI 2012 cystatin C (mL/min/1.73 m²)	Female	Scys ≤ 0.8	eGFR = 133 × (Scys/0.8)^{– 0.499} × 0.996^age × 0.932
	Female	Scys > 0.8	eGFR = 133 × (Scys/0.8)^{– 1.328} × 0.996^age × 0.932
	Male	Scys ≤ 0.8	eGFR = 133 × (Scys/0.8)^{– 0.499} × 0.996^age
	Male	Scys > 0.8	eGFR = 133 × (Scys/0.8)^{– 1.328} × 0.996^age
CKD-EPI 2021 creatinine-cystatin C (mL/min/1.73 m²)	Female	Scr ≤ 0.7	Scys ≤ 0.8	eGFR = 135 × (Scr/0.7)^-0.219 × (Scys/0.8)^-0.323 × 0.9961^age × 0.963
		Scr ≤ 0.7	Scys > 0.8	eGFR = 135 × (Scr/0.7)^-0.219 × (Scys/0.8)^-0.778 × 0.9961^age × 0.963
		Scr > 0.7	Scys ≤ 0.8	eGFR = 135 × (Scr/0.7)^-0.544 × (Scys/0.8)^-0.323 × 0.9961^age × 0.963
		Scr > 0.7	Scys > 0.8	eGFR = 135 × (Scr/0.7)^-0.544 × (Scys/0.8)^-0.778 × 0.9961^age × 0.963
	Male	Scr ≤ 0.9	Scys ≤ 0.8	eGFR = 135 × (Scr/0.9)^-0.144 × (Scys/0.8)^-0.323 × 0.9961^age
		Scr ≤ 0.9	Scys > 0.8	eGFR = 135 × (Scr/0.9)^-0.144 × (Scys/0.8)^-0.778 × 0.9961^age
		Scr > 0.9	Scys ≤ 0.8	eGFR = 135 × (Scr/0.9)^-0.544 × (Scys/0.8)^-0.323 × 0.9961^age
		Scr > 0.9	Scys > 0.8	eGFR = 135 × (Scr/0.9)^-0.544 × (Scys/0.8)^-0.778 × 0.9961^age

Age (year); weight (kg).

eGFR: Estimated glomerular filtration rate; Scr: Serum creatinine (mg/dL); MDRD: Modification of Diet in Renal Disease; CKD-EPI: Chronic Kidney Disease Epidemiology Collaboration; Scys: Serum cystatin C (mg/L).

Citation: Tran TTT, Ha TK, Phan NM, Le MV, Nguyen TH. Detection of decline in estimated glomerular filtration rate in patients with type 2 diabetes by cystatin C-based equations. World J Nephrol 2024; 13(4): 95761
URL: https://www.wjgnet.com/2220-6124/full/v13/i4/95761.htm
DOI: https://dx.doi.org/10.5527/wjn.v13.i4.95761