Clinicopathological features and medium-term outcomes of histologic variants of primary focal segmental glomerulosclerosis in adults: A retrospective study

Table 3 Responses to treatment and final clinical outcomes of focal segmental glomerulosclerosis morphologic variants in patients who received treatment, n (%)

Outcomes	All patients (n = 302)	NOS (n = 160)	TIP (n = 89)	COL (n = 53)	P value
Complete remission	84 (27.8)	40 (25.0)	42 (47.1)	2 (3.7)	< 0.001
Partial remission	49 (16.2)	27 (16.8)	11 (12.4)	11 (20.8)	0.005
No remission	169 (55.9)	93 (58.1)	36 (40.4)	40 (75.5)	< 0.001
Relapse	40 (13.2)	27 (16.9)	9 (10.1)	4 (7.5)	0.029
Final eGFR (mL/min/1.73 m2), mean ± SD	92.1 ± 57.7	94.1 ± 59.1	110.3 ± 52.8	60.0 ± 46.9	< 0.001
Doubling of serum creatinine at last follow-up	30 (9.9)	16 (10.0)	1 (1.1)	13 (24..5)	< 0.001
Kidney failure	36 (11.19)	13 (8.1)	0 (0.0)	23 (43.3)	< 0.001
Hemodialysis	18 (5.9)	5 (3.1)	0 (0.0)	13(24.5)	< 0.001
Expired	4 (1.3)	3 (1.8)	0 (0.0)	1 (1.8)	0.429

NOS: Not otherwise specified; TIP: Tip; COL: Collapsing; eGFR: Estimated glomerular filtration rate.