Antihypertensive prescribing patterns in non-dialysis dependent chronic kidney disease: Findings from the Salford Kidney Study

Table 10 Cox regression analysis demonstrating associations between the prescription of three or more antihypertensive agents with all-cause mortality

Analysis	HR (95%CI)1	P value1
Univariate model	1.55 (1.41-1.69)	< 0.001
Multivariate model 12	1.33 (1.21-1.45)	< 0.001
Multivariate model 23	1.23 (1.12-1.35)	< 0.001
Multivariate model 34	1.15 (1.04-1.27)	0.006

¹Absolute number for hazard ratio alongside corresponding 95% confidence interval and P value.

²Multivariate model 1: adjusted for age, sex, ethnicity, smoking status, and alcohol intake.

³Multivariate model 2: adjusted for all covariates of model 1 plus diabetes, any cardiovascular disease (ischemic heart disease or myocardial infarction or congestive cardiac failure or cerebrovascular accident or peripheral vascular disease), and blood pressure control < 140/90 mmHg.

⁴Multivariate model 3: adjusted for all covariates of model 2 plus estimated glomerular filtration rate and urine albumin-creatinine ratio.

HR: Hazard ratio; 95%CI: 95% confidence interval.