Renal biopsy reports in nephritic syndrome: Update

Table 2 Meta-analysis of the estimated incidence (95% confidence interval) of nephropathy diagnoses for patients with nephritic syndrome

Nephropathy	Highest rate (%)	Lowest rate (%)	Pediatric (%)	Adults (%)	Elderly (%)	General (%)	NiS-NS (%)	Total (%)
MGN	M.E. 10.2 (8.1-12.3)	Eu. 2.4 (1.9-2.8)	2.5 (0.4-4.6)	7.3 (6.9-7.7)1	2.3 (0-5.7)	4.4 (3.9-4.8)	11.7 (6.8-16.6)	5.9 (5.6-6.2)
IgA nephropathy	E.A. 50.1 (49.3-50.8)	S.A. 9.8 (7.6-11.2)	11 (8.2-13.7)	42.6 (41.9-43.4)1	5.9 (2.8-8.9)	37.4 (36.4-38.3)	3.7 (0-7.8)	38.3 (37.7-38.9)
Henoch Schönlein purpura2	Eu. 10.7 (2.8-18.6)	S.A. 1.9 (0.5-3.2)	6.3 (3-9.6)	7.6 (7.2-8.1)1	-	1.2 (0-2.6)	-	7.1 (6.6-7.5)
FSGS	M.E. 11.4 (9.3-13.4)	E.A. 1.6 (1.4-1.8)	3.4 (1.7-5.1)	1.6 (1.4-1.8)	3.9 (0.9-6.8)	4.3 (3.9-4.7)1	19.4 (13-25.8)	2.1 (1.9-2.2)
Lupus nephropathy	L.A. 44.6 (33.7-55.5)	Eu. 4.6 (4-5.3)	12.9 (9.8-15.9)1	9.3 (8.9-9.8)	5.3 (1.6-8.9)	5.4 (4.7-6.1)	10.4 (6.1-14.7)	8.2 (7.8-8.6)
MCD	S.A. 4.4 (1.8-6.9)	E.A. 0.7 (0.5-0.8)	5.7 (0-12.6)1	0.7 (0.6-0.8)	-	1.6 (1.2-1.9)	-	0.8 (0.7-0.9)
Crescentric GN	USCA 18.9 (16.6-21.3)	E.A. 0.6 (0.2-1)	3.4 (1.7-5)	1.7 (1.3-2.2)	45.7 (36.6-54.8)1	6.4 (5-7.9)	-	2.3 (1.9-2.7)
MPGN	USCA. 12.9 (4.8-20.9)	E.A. 0.9 (0.7-1.1)	14.2 (11.4-17)	1 (0.9-1.2)	17.5 (12.1-22.9)1	4.1 (3.5-4.8)	9.2 (4.2-13.5)	1.3 (1.1-1.4)
Amyloidosis	Eu. 1.2 (0.5-1.9)	E.A. 0.8 (0.6-1.1)	0.6 (0-1.4)	0.4 (0.1-0.7)	-	2 (1.6-2.4)1	-	0.9 (0.7-1.1)
Diabetic nephropathy	Eu. 3.9 (3.3-4.5)	S.A. 0.8 (0-1.6)	-	1.5 (1.3-1.7)	3.1 (0-6.2)1	2.7 (2.2-3.2)	-	1.7 (1.5-1.9)
TID	L.A. 27.8 (4.9-50.7)	E.A. 0.6 (0.5-0.7)	3.5 (1.1-5.8)	0.6 (0.5-0.8)	6.7 (1.8-11.7)1	2.3 (1.3-3.3)	-	0.7 (0.5-0.8)
Vascular nephropathy	L.A. 19.3 (10.6-27.9)	M.E. 0.8 (0.1-1.5)	2.9 (0.4-5.4)	2.2 (1.9-2.4)	4.3 (1.4-7.2)1	3 (2.5-3.5)	-	2.3 (2.1-2.5)
Nephroangiosclerosis2	M.E. 20 (0-57.8)	S.A. 0.7 (0-1.6)	-	1.7 (1.5-1.9)	22.7 (9.8-35.6)1	3.3 (2.7-3.9)	-	1.8 (1.6-2)
Hereditary nephropathy	Eu. 3.4 (0.9-5.9)	E.A. 0.7 (0.6-0.9)	2.9 (0.8-5)1	0.7 (0.6-0.9)	-	-	-	0.8 (0.6-0.9)
Unspecific Proliferative GN	S.A. 34.2 (31.5-37)	E.A. 1.4 (1.2-1.6)	23.4 (20-26.9)1	1.6 (1.4-1.8)	20.4 (9.7-31)	11.7 (9.8-13.6)	14.1 (9-19.2)	1.7 (1.6-1.9)
MesPGN2	E.A. 10 (8.2-11.8)	S.A. 4.5 (3.1-5.9)	7.5 (5.2-9.7)1	5.3 (4.5-6.2)	-	6.2 (4.5-8)	9.2 (4.2-13.5)	5.7 (5-6.5)
Unspecific Paraproteinemia	S.A. 11.8 (1.6-22)	E.A. 0.6 (0.4-0.7)	-	0.6 (0.4-0.7)	11.8 (1.6-22)1	-	-	0.6 (0.4-0.7)

¹Zero incidence rates have been omitted to report; the frequency (95% confidence interval) are those representing the highest for each diagnosis.

²Subsections of their abovementioned entity as described previously[2].

E.A.: East Asia; Eu.: Europe; FSGS: Focal and segmental glomerulosclerosis; L.A.: Latin America; MCD: Minimal change disease; M.E.: Middle East; MesPGN: Mesangial proliferative glomerulonephritis; MGN: Membranous glomerulonephritis; MPGN: Membranoproliferative glomerulonephritis; NiS-NS: Patients simultaneously presenting with nephritic- & nephrotic syndromes; S.A.: South Asia; TID: Tubulointerstitial diseases; USCA: United States-Canada-Australia.