Peritoneal dialysis associated infections: An update on diagnosis and management

Table 3 Exit site management

Ref.	No.	Trial/protocol	Results	Comments
Mahaldar et al[132]	100	Mupirocin vs Gentamicin	No difference in ESI rates	Trend to higher peritonitis in gentamicin group. Retrospective study
Wong et al[133]	154	Mupirocin vs Control	Mupirocin effective in preventing G+ve peritonitis	Randomised controlled trial. No adverse effects with mupirocin
Fong[122]	69	Providone-iodine vs Control	PVI 2.9%	Nasal carriers high in PVI group!
			Control 8.8%	Randomised controlled trial
Bernardini et al[134]	133	Gentamicin (67) vs Mupirocin (66)	0.23 peritonitis episodes per patient-year (gentamicin) vs 0.54 for mupirocin	Time to first infection longer with Gentamicin
McQuillan et al[135]	201	Polysporin Triple Ointment (P3) vs Mupirocin	No difference in time to ESI or peritonitis but higher rate of fungal infections and more redness of exit site in P3 group	Multicentre randomised controlled trial

ESI: Exit site infection.