Matrix metalloproteases and their tissue inhibitors in non-alcoholic liver fibrosis of human immunodeficiency virus-infected patients

Table 6 Independent predictors of different fibrosis indexes

	TE	APRI	Forns	FIB-4	YFPI
Higher MMP-2 levels	0.001	0.0001	0.03	0.0009	0.004
Higher TIMP-2 levels	0.016	0.0001	0.024	0.0002	-
Lower MMP-9 levels	0.023	0.016	-	0.03	0.043
Lower current CD4 counts	-	0.032	0.037	0.043	-
Older age	-	-	0.004	0.05	-
% of the index accounted for by the model	20.00%	35.30%	23.30%	33.50%	20.70%

Numbers represent P values. HCV: Hepatitis C virus; MMP: Matrix metalloprotease; TE: Transient elastometry; YFPI: Yearly fibrosis progression index (only for HCV-infected patients); APRI: AST to Platelet Ratio Index; TIMP: Tissue inhibitor of metalloprotease.