Key role of human leukocyte antigen in modulating human immunodeficiency virus progression: An overview of the possible applications

Figure 1 Human leukocyte antigen class I tridimensional structure. Crystal structure of the HLA-B*57:03 (PDB ID: 2YPK); HLA α-chain in gray, β2-microglobulin in blue, the peptide in orange. A: HLA class I overall structure; B: HLA class I peptide binding pocket. In red is shown the HLA pocket B, in green HLA pocket F the most polymorphic regions in HLA peptide binding pocket. The figure has been made using WebLab Viewer Pro 3.7. HLA: Human leukocyte antigen.