Architecture and biogenesis of plus-strand RNA virus replication factories

Figure 4 Primary membrane source and host cell factors subverted by different plus-strand RNA viruses. A eukaryotic cell and (endo)membrane organelles are depicted schematically as indicated on the bottom. Viruses are displayed next to their primary membrane source organelle and recruited host cell factors involved in lipogenesis and membrane remodeling are denoted in italics adjacent to each virus name. FHV: Flock-house virus; PSTPIP2: Proline-serine-threonine phosphatase interacting protein 2; HCV: Hepatitis C virus; SREBP: Sterol regulatory element-binding protein; PI4K: Phosphatidylinositol-4-kinase; GBF1: Golgi-specific BFA-resistance guanine nucleotide-exchange factor 1; BMV: Brome mosaic virus; FASN: Fatty acid synthase.