Retrospective Study
Copyright ©The Author(s) 2024.
World J Virol. Dec 25, 2024; 13(4): 96573
Published online Dec 25, 2024. doi: 10.5501/wjv.v13.i4.96573
Table 2 Hospitalized vs non-hospitalized pregnant women, n (%)
Hospitalized (n = 15)
Not hospitalized (n = 45)
P value
Demographics
    Age median (IQR)34 (23-40)29.67 (26-34)0.36
    Former smokers 2 (13.3)6 (13.3)0.584
    BMI > 30 3 (20)0 (0)0.013
    At least one co-morbidity 4 (26.6)6 (13.3)0.25
    Gestational week median (IQR)30 (26-36)36 (34-38)0.031
Clinical manifestations
    Asymptomatic0 (0)27 (37.7)< 0.001
    Days from onset median (IQR)7 (2-9)2 (2-3)0.006
    Fever (symptomatic)10 (66.6)8 (17.7)0.2
    Dyspnoea (symptomatic)11 (73.3)0 (0)< 0.001
    Cough (symptomatic)11 (73.3)8 (17.7)0.09
    Contractions (symptomatic)2 (13.3)16 (35.5)0.026
Disease severity
    WHO CPS median (IQR)5 (5-6)2 (1-4)< 0.001
    P/F < 40010 (66.6)3 (20)< 0.001
    Need for NIV 6 (13.3)0 (0)< 0.001
    Need for IMV4 (8.8)0 (0)< 0.001
Pharmacological management
    Corticosteroids13 (86.6)12 (26.6)< 0.001
    Remdesivir 8 (53.3)5 (11.1)0.02
Pregnancy outcomes
    Preterm delivery5 (33.3)13 (28.8)0.745
    Composite adverse perinatal 5 (33.3)6 (13.3)0.09
Laboratory values median (IQR)
    WBC (Κ/μL)6980 (5580-8320)9110 (7380-11150)0.01
    LYMPH (Κ/μL)1.142 (0.785-1.570)1.300 (1.020-1.880)0.102
    CPK (ng/mL)69 (20-94)65.5 (35-164)0.179
    LDH (IU/L)318 (258-376)210 (178-283)0.001
    CRP (mg/dL)5.94 (2.09-9.81)2.34 (1.02-4.47)0.028
    Ferritin (ng/mL)149 (101-140)74 (34.5-95.5)0.001
    D-Dimers (μg/mL)1.470 (0.670-2.180)1.492 (1.045-2.215)0.303
WHO CPS: World Health Organization Clinical Progression Score for COVID-19; BMI: Body mass index; P/F: PaO2/FiO2 ratio; NIV: Non-invasive ventilation; IMV: Invasive mechanical ventilation; WBC: White blood cells; LYMPH: Lymphocyte count; CPK: Creatine phosphokinase; LDH: Lactate dehydrogenase; CRP: C-reactive protein.