Transient elastography and diffusion-weighted magnetic resonance imaging for assessment of liver fibrosis in children with chronic hepatitis C

Table 3 Correlation of fibrosis and activity with different studied parameters

Parameters	Fibrosis		Activity
	R value	P value	R value	P value
Age in yr	0.068	0.594	0.159	0.208
Aspartate transaminase (U/L)	-0.044	0.751	0.192	0.160
Alanine transaminase (U/L)	0.092	0.501	0.242	0.073
Prothrombin time (second)	-0.066	0.637	-0.184	0.188
Hemoglobin (g/dL)	0.041	0.764	-0.050	0.718
White blood cells as × 103/mm3	0.680	0.620	0.015	0.913
Platelets as × 103/mm3	0.047	0.731	-0.032	0.815
LSM (kPa)	0.338	0.008	0.385	0.002
Liver ADC (mm2/s)	-0.299	0.086	-0.281	0.840
Spleen ADC (mm2/s)	-0.212	0.145	-0.019	0.897
Normalized liver ADC	-0.064	0.653	-0.148	0.300
APRI score	-0.003	0.984	-0.088	0.549
FIB-4 score	-0.128	0.376	0.148	0.305

ADC: Apparent diffusion coefficient; APRI: Aspartate aminotransferase-to-platelet ratio; FIB-4: Fibrosis-4 index; LSM: Liver stiffness measurement.