Driving forces of continuing evolution of rotaviruses

Figure 3 Cartoon representation of Rotavirus strategy to evade the host innate immune system. OAS: Oligoadenylate synthase; β-TrCP: Beta-transducin repeats-containing proteins; IRF: Interferon regulatory factor; STAT: Signal transducer and activator of transcription; PABP: Poly(A) binding protein; ISRE: Interferon-stimulated response element; eIF4G: Eukaryotic translation initiation factor 4G.