Driving forces of continuing evolution of rotaviruses

Figure 2 Reassortment mechanism of rotaviruses group A (RVA). A: Diagrammatic representation of the emergence of a novel reassortant strain with genes derived from two parental strains; B: Reassortment in RVA begins with the synthesis of positive-sense RNA. A total of newly-synthesized 11 positive segments of RNA will form a complex of supramolecular structures and be immediately assembled by virion particles that grow through the encapsidation process. The polymerase enzyme then converts positive RNA into dsRNA shortly after the encapsidation process.