Cytomegalovirus infection in non-immunocompromised critically ill patients: A management perspective

Table 3 Polymerase chain reaction tests for cytomegalovirus and the cut offs used in various studies

Ref.	Test	Threshold copies/ml	Threshold as per IU/mL
Papazian et al[15]	PCR		500 IU/mL whole blood
Park et al[51]	RT-PCR	> 270 copies/mL in whole blood
Hraiech et al[17]	PCR	Copy number > 500/mL CMV	“High reactivation” for viral loads greater than or equal to 1000 IU/mL or “low reactivation” for viral loads of 100–999 IU/mL
Zhang et al[29]	PCR	Copies > 500/mL
Osawa et al[12]		Copies > 500 copies/mL
Ong et al[10]			100 IU/mL

CMV: Cytomegalovirus; IU: International units; RT- PCR: Reverse transcription polymerase chain reaction.