COVID-19 frequency and clinical course in children with asthma

doi:10.5501/wjv.v12.i5.272

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World Journal of Virology

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2220-3249

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

World J Virol. Dec 25, 2023; 12(5): 272-285
Published online Dec 25, 2023. doi: 10.5501/wjv.v12.i5.272

Table 3 Evaluation of various laboratory parameters in different groups of asthma patients

	Others⁴, (n = 169)		Vaccinated patients, (n = 57)		Atopic patients, (n = 64)		P value	ES
	n	mean ± SD	n	mean ± SD	n	mean ± SD	P value	ES
Age	269	16.57 ± 4.16^a	57	18.86 ± 3.43^b	64	15.77 ± 3.87^a	< 0.001¹^,³	0.049
COVID-19 age	269	14.71 ± 4.09^a	57	17.28 ± 3.55^b	64	13.83 ± 3.75^a	< 0.001¹^,³	0.063
Hemoglobin	68	13.13 ± 1.44	12	13.66 ± 1.57	17	12.96 ± 1.83	0.456¹	0.017
Leucocyte	67	6803.79 ± 2825.88	12	6162.5 ± 2173.43	17	7068.24 ± 4155.47	0.903²	0.007
Neutrophil	67	4119.30 ± 2601.78	12	3563.33 ± 1721.86	17	3762.94 ± 2089.5	0.920²	0.008
Lymphocyte	68	1861.94 ± 939.88	12	1924.17 ± 1008.59	17	2503.53 ± 2908.44	0.915²	0.027
Eosinophil	67	141.91 ± 171.81	12	157 ± 149.52	17	146.29 ± 190.62	0.327²	0.001
Platelet	68	245864.71 ± 74049.74	12	273750 ± 77324.73	17	232352.94 ± 66343.75	0.368²	0.024
CRP	62	10.28 ± 20.13^a	8	7.84 ± 5.34^a	14	2.85 ± 2.41^b	0.016²^,³	0.025
Sedimentation	5	11 ± 7.52	2	5 ± 1.41			-	-
AST	63	25.58 ± 11.28	12	22.92 ± 5.23	16	27.06 ± 12.68	0.829²	0.011
ALT	63	19.13 ± 13.72	12	20.17 ± 14.83	16	20.06 ± 17.47	0.908²	0.001
Urea	61	21.5 ± 6.2	12	21.35 ± 7.18	16	22.45 ± 6.81	0.727²	0.004
PT	33	12.07 ± 1.24	4	11.65 ± 0.95	8	12.49 ± 1.25	0.512¹	0.031
aPTT	31	28.87 ± 3.4	4	28.53 ± 1.97	7	28.96 ± 2.17	0.974¹	0.001
D-Dimer	48	508.98 ± 953.33	9	334.78 ± 206.13	11	265.18 ± 128.16	0.647²	0.015
LDH	47	243.44 ± 88.75	8	202.59 ± 54.89	12	225.16 ± 87.56	0.312²	0.027
Total IgE	37	176.05 ± 252.36^a	2	174.5 ± 144.96^a^,^b	13	1127.04 ± 1325.03^b	0.009²^,³	0.274

¹P values for one way ANOVA.

²P values for Kruskal Wallis test.

³According to the results of the pairwise comparison test, in addition to group statistics, there is no statistically significant difference between groups with the same superscript letter (a/a or b/b), but there is a statistically significant difference between groups with different superscript letters (a/b).

⁴This column includes asthma patients who are neither atopic nor vaccinated.

ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; aPTT: Activated partial thromboplastin time; COVID-19: Coronavirus disease 2019; CRP: C-reactive protein; LDH: Lactate dehydrogenase.

Citation: Özata MC, Dikici Ü, Özdemir Ö. COVID-19 frequency and clinical course in children with asthma. World J Virol 2023; 12(5): 272-285
URL: https://www.wjgnet.com/2220-3249/full/v12/i5/272.htm
DOI: https://dx.doi.org/10.5501/wjv.v12.i5.272