COVID-19 and hemolysis, elevated liver enzymes and thrombocytopenia syndrome in pregnant women - association or causation?

Figure 2 Pathogenesis of coronavirus disease 2019. Severe acute respiratory syndrome coronavirus 2 entry into the host cell is mediated through its binding with angiotensin converting enzyme 2 receptor and transmembrane serine protease 2 enzyme. The pathogenetic pathways include direct cytotoxicity, endothelialitis, (endothelial damage), dysregulated host-immune response and renin-angiotensin aldosterone system. Respiratory system is the primary target organ, but other systems are involved either with direct invasion or in response of systemic dysregulated immune response. SARS-CoV-2: Severe acute respiratory syndrome coronavirus 2; ACE2: Angiotensin converting enzyme 2; TMPRSS2: Transmembrane serine protease 2; RAAS: Renin angiotensin aldosterone system; ACS: Acute coronary syndrome; AKI: Acute kidney injury.