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©The Author(s) 2022.
World J Virol. Sep 25, 2022; 11(5): 375-390
Published online Sep 25, 2022. doi: 10.5501/wjv.v11.i5.375
Published online Sep 25, 2022. doi: 10.5501/wjv.v11.i5.375
Biomarker in COVID | Study | Recommendation |
Presepsin | Favaloro et al[73] | Presepsin elevation is a reliable biomarker in COVID-19 |
Park et al[74] | A four-to-five-fold increase in presepsin correlates with disease severity in COVID-19 | |
Lippi et al[75] | ||
Koyjit et al[73] | ||
Fukada et al[77] | Presepsin is elevated in severe cases of SARS-CoV-2 associated respiratory complications | |
Park et al[74] | Presepsin level at 717pg/ml is a significant predictor of 30-day mortality | |
Dell’Aquila et al[79] | A threefold rise in presepsin has been identified as a very specific indicator of 30-day mortality | |
Lippi et al[75] | ||
Soluble ST2 (sST2) | Omland et al[87] | Robust association between baseline sST2 level and disease severity along with poor outcome |
Huang et al[88] | Baseline sST2 is associated with a worse prognosis | |
Ragusa et al[89] | Circulating level of sST2 can be used as a discharge prognosticator | |
Galectin-3 | Caniglia et al[96] | Gal-3 is considerably higher in bronchoalveolar immune cells in patients with severe COVID-19 disease |
Portacci et al[97] | Higher galectin-3 is associated with worse outcomes and shorter survival | |
Copeptin | Gregoriano et al[100] | Serum copeptin level above 20 Pmol/L had sensitivity of > 88% to predict severe COVID-19 |
Hammad et al[101] | Serum copeptin level above 18.5 Pmol/L had sensitivity of > 93% and specificity of 100% to predict severe COVID-19 | |
GDF 15 | Apfel et al[103] | Higher levels of GDF-15 correlated with severity of COVID-19 |
- Citation: Muthyala A, Sasidharan S, John KJ, Lal A, Mishra AK. Utility of cardiac bioenzymes in predicting cardiovascular outcomes in SARS-CoV-2. World J Virol 2022; 11(5): 375-390
- URL: https://www.wjgnet.com/2220-3249/full/v11/i5/375.htm
- DOI: https://dx.doi.org/10.5501/wjv.v11.i5.375