Serological diagnosis of Epstein-Barr virus infection: Problems and solutions

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Feb 12, 2012 (publication date) through Feb 21, 2025

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World Journal of Virology

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2220-3249

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Virol . Feb 12, 2012; 1(1): 31-43
Published online Feb 12, 2012. doi: 10.5501/wjv.v1.i1.31

Table 2 Interpretation of Epstein-Barr virus serological profiles in immunocompetent patients

Anti-EBV antibodies			Interpretation
VCA IgM	VCA IgG	EBNA-1 IgG
Negative	Negative	Negative	No immunity
Positive	Negative	Negative	Acute infection or non-specificity¹
Positive	Positive	Negative	Acute infection
Negative	Positive	Positive	Past infection
Negative	Positive	Negative	Acute or past infection¹
Positive	Positive	Positive	Late primary infection or reactivation¹
Negative	Negative	Positive	Past infection or non-specificity¹

¹Further testing required.

Citation: De Paschale M, Clerici P. Serological diagnosis of Epstein-Barr virus infection: Problems and solutions. World J Virol 2012; 1(1): 31-43
URL: https://www.wjgnet.com/2220-3249/full/v1/i1/31.htm
DOI: https://dx.doi.org/10.5501/wjv.v1.i1.31