Impact of recipient functional status on 1-year liver transplant outcomes

Table 5 Association between pre-transplant functional status and 1-year (all-cause) post-transplant mortality, Scientific Registry of Transplant Recipients 2005–2014 (n = 38278^a)

Functional impairment/disability	Hazard Ratio (95%CI)
	1-Yr		Day 0-30c		Day 31-365d
	Unadjusted	Adjustedb	Unadjusted	Adjustedb	Unadjusted	Adjustedb
Severe	1.94 (1.77-2.13)	1.73 (1.56-1.91)	2.40 (1.99-2.89)	2.10 (1.71-2.59)	1.82 (1.64-2.02)	1.62 (1.45-1.82)
Moderate	1.38 (1.27-1.51)	1.32 (1.21-1.44)	1.60 (1.34-1.92)	1.53 (1.27-1.83)	1.33 (1.20-1.46)	1.26 (1.15-1.40)
None	Referent		Referent		Referent

^aAdjusted model n = 380762 [missing albumin (n = 1) or donor body mass index (n = 200)];

^bAdjusted for recipient age, sex, race, insurance, body mass index (BMI), diabetes, previous abdominal surgery, liver disease, MELD, albumin, portal vein thrombosis, dialysis; donor age, race, BMI, donor type (living or deceased) and cause of death, donation after cardiac death, allocation type, cold ischemia time ≥ 8 hours; interactions: recipient BMI and diabetes, recipient hepatitis C and portal vein thrombosis, recipient hepatitis C and donor age;

^cPostoperative day 0-30: n = 38,278; 881 deaths;

^dPostoperative day 31-365: n = 37352; 2714 deaths. BMI: Body mass index; CI: Confidence interval; MELD: Model for End-Stage Liver Disease.