Histopathological characteristics and causes of kidney graft failure in the current era of immunosuppression

Table 1 Baseline characteristics, n (%)

Baseline characteristics
Total number of graft failure	329 (100)
Female gender	127 (39)
Mean age at the time of transplant (yr)	42.2 ± 13.7
Caucasian	253 (77)
Causes of end stage renal disease:
Glomerulonephritis	99 (30)
Diabetes	71 (22)
Hypertension	35 (11)
Polycystic kidney disease	34 (10)
Congenital disorder	9 (3)
Other	81 (25)
Mean number of transplants (Range 1-3)	1.29 ± 0.59
Living donor transplant	108 (33)
Induction Immunosuppression:
Basiliximab	179 (54)
Thymoglobulin	52 (16)
Alemtuzumab	66 (20)
Other	32 (10)
Organ failure method:
Resumption of dialysis	319 (97)
Re-transplantation (preemptive re-transplant)	10 (3)
DSA within a year prior to the graft failure:
Present	184 (56)
Absent	89 (27)
Not tested	56 (17)
Mean graft survival (yr)	4.9 ± 4.4
Mean interval between biopsy and graft failure (d)	106.5 ± 104.6

DSA: Donor-specific antibodies.