Copyright
©The Author(s) 2019.
World J Transplant. Aug 26, 2019; 9(4): 62-80
Published online Aug 26, 2019. doi: 10.5500/wjt.v9.i4.62
Published online Aug 26, 2019. doi: 10.5500/wjt.v9.i4.62
Ref. | Pats | f/u | Findings/timing of biopsy-technology |
Hoffmann et al[28], 2002 | 24 | 1 h | IRI injury ass w increased adhesion, chemotaxis, apoptosis, monocyte recruitment/activation transcripts.Post-reperfusion/RT-PCR |
Hauser et al[29],2004 | 36 | 1 | Increased Communication, apoptosis, inflammation |
Kainzet al[30],2004 | 10 | 1 | DD kidneys distinctly different transcripts in the TI but not in the G compartment compared to LD. End of CIT/microarrays |
Avihingsanon et al[31],2005 | 75 | 6 | 15 selected genes associated with outcomes, included DGF, REJ and 6 mofunction. Post-reperfusion/RT-PCR |
Kainzet al[32],2007 | 31 | 12 | Increased immunity, signal transduction, oxidative stress response associated with lower 1-year function |
Park et al[33],2007 | 15 | 12 | Increased inflammation and immune response at 1-year in uncomplicated grafts |
Mas et al[34],2008 | 33 | 3 | Increased immunity, inflammation and apoptosis genes associated with DGF. End of CIT/microarrays |
Mueller et al[35],2008 | 87 | 12 | Increased acute phase, complement, chemochines and reduced metabolism, transporters in DD versus LD, transcriptome identifies risk for DGF better than clinical ± histological markers. Post-reperfusion/ microarrays |
Perco et al[36], 2009 | 82 | 12 | Increasedimmunity/defense, communication, apoptosis in damaged kidneys, CADI score + clinic explained 14%, 3 biomarkers 28% of 1-year creatinine variability. End of CIT/ microarrays |
Naesens et al[37], 2009 | 28 | 36 | Complement genes differ between LD and DD and are associated with early and late function. End of CIT and post-transplant/ microarrays |
Bodonyi-Kovacs et al[38], 2010 | 75 | 48 | Pre-selected genes associated with 2-year graft function. Post-reperfusion/ RT-PCR |
Cravedi et al[39], 2010 | 49 | 12 | LDvs DD differ by inflammation, donor age and ITGB2 prognostic for 1-year function. Post-reperfusion/RT-PCR |
- Citation: Salvadori M, Tsalouchos A. Histological and clinical evaluation of marginal donor kidneys before transplantation: Which is best? World J Transplant 2019; 9(4): 62-80
- URL: https://www.wjgnet.com/2220-3230/full/v9/i4/62.htm
- DOI: https://dx.doi.org/10.5500/wjt.v9.i4.62