Renal transplants from older deceased donors: Is pre-implantation biopsy useful? A monocentric observational clinical study

Table 2 Baseline characteristics of donors and recipients in the 3 transplant categories

Transplant category1	SKT(1-4)	SKT(> 4)	DKT
n	102	30	53
Donors, M/F	54/48	16/14	29/24
Donor age, yr (mean, SD)	68.9 ± 5.7	66.9 ± 6.7	75.3 ± 5.0b
Score of transplanted graft, median (IQR)	3 (3-4)d	5 (5-6)a	5 (4-5)
Donor comorbidities
Donor age > 70 yr, n (%)	47 (46)	8 (27)	47 (89)b
Arterial hypertension	40 (39)	21 (70)	34 (64)
Diabetes	9 (9)	6 (20)	7 (13)
Cerebrovascular cause of death	33 (32)	17 (57)	29 (55)
KDPI1	89.4 ± 8.0	89.9 ± 9.2	96.9 ± 3.4b
KDRI1	1.65 ± 0.27	1.7 ± 0.33	2.02 ± 0.31b
Recipients, M/F	68/34	20/10	37/16
Recipient age (mean ± SD, yr)	61.0 ± 7.2	60.2 ± 6.0	67.3 ± 4.6b
Years on dialysis, median (IQR)	3.5 (0.1-13.5)	3.4 (0.8-9.5)	2.1 (0.3-8.5)b
Dialysis mode, n (%)
Hemodialysis	84 (82)	25 (83)	40 (75)
Peritoneal dialysis	16 (16)	5 (17)	12 (23)
Pre-emptive	2 (2)	0	1 (2)
Renal disease n (%)1
GN/systemic	35 (34)	10 (34)	19 (36)
ADPKD	24 (23)	4 (13)	6 (11)
Vascular/hypertension	10 (10)	3 (10)	3 (6)
Diabetes	11 (11)	4 (13)	7 (13)
Other	14 (14)	6 (20)	12 (23)
Unknown	8 (8)	3 (10)	6 (11)
1st-2nd-3rd Tx	95-6-1	28-2-0	51-2-0
HLA-MM (median, IQR)	4 (3-5)	4 (3-5)	4 (4-5)
CITa (mean ± SD, h)	15.0 ± 3.6	15.9 ± 4.2	16.1 ± 3.1

¹SKT_(1-4), solitary kidney transplant, histologic score 1 to 4; SKT_{(> 4)}: Solitary kidney transplant, histological score 5 or higher; DKT: Dual kidney transplant, histological score 5 to 7; KDPI and KDRI: Kidney Donor Profile Index and Kidney Donor Risk Index; GN/systemic: Glomerulonephritis or systemic immunological disorder; CIT: Cold ischemia time.

^bP < 0.01 vs SKT (both categories);

^dP < 0.001 vs SKT_{(> 4)} and DKT;

^aP < 0.039 vs DKT.