Risk factors and clinical indicators for the development of biliary strictures post liver transplant: Significance of bilirubin

Table 1 Baseline donor and recipient characteristics n (%)

Characteristics	Overall (n = 296)	Biliary strictures (n = 45)	Nil biliary strictures (n = 251)	P value
Donor characteristics
Age (yr)	42 (28-54)	48 (40-57)	42 (27-54)	NS
Gender (male)	165 (55.7)	25 (55.6)	140 (55.8)	NS
BMI (kg/m2)				NS
< 18.5	5 (1.7)	0 (0.0)	5 (2.0)
18.5-24.9	137 (46.3)	18 (40.0)	119 (47.4)
25-29.9	117 (39.5)	20 (44.4)	97 (38.6)
> 30	37 (12.5)	7 (15.5)	30 (12.0)
Donor type				NS
Donation after brain death	285 (96.3)	44 (97.8)	241 (96.0)
Donation after circulatory death	11 (3.7)	1 (2.2)	10 (4.0)
Cause of death				NS
Stroke	154 (52.0)	29 (64.4)	125 (49.8)
Hypoxia	43 (14.5)	6 (13.3)	37 (14.7)
Accident	37 (12.5)	3 (6.7)	34 (13.5)
Other	62 (20.9)	7 (15.6)	55 (21.9)
Recipient characteristics
Age at transplant (yr)	52 (45-57)	53 (40-58)	52 (45-57)	NS
Gender (male)	207 (69.9)	31 (68.8)	176 (70.1)	NS
BMI (kg/m2) (n = 267)	267	44	223	NS
Underweight (≤ 18.5)	5 (1.9)	0 (0.0)	5 (2.0)
Normal weight (18.5-24.9)	94 (35.2)	17 (38.6)	77 (30.7)
Overweight (25-29.9)	93 (34.8)	15 (34.1)	78 (31.1)
Obese ≥ 30	75 (28.1)	12 (27.3)	63 (25.1)
Reason for transplant				NS
Viral hepatitis (B, C) ± hepatocellular carcinoma	124 (41.9)	19 (42.2)	105 (41.8)
Hepatocellular carcinoma without hepatitis	22 (7.4)	1 (2.2)	21 (8.4)
Alcohol	33 (11.1)	6 (13.3)	27 (10.8)
Biliary1	29 (9.8)	8 (17.8)	21 (8.4)
Non-alcoholic steatohepatitis	14 (4.7)	3 (6.7)	11 (4.4)
Acute/fulminant liver failure	12 (4.1)	2 (4.4)	10 (4.0)
Complications first transplant	21 (7.1)	3 (6.7)	18 (7.2)
Other	41 (13.8)	3 (6.7 )	38 (15.1)
Previous transplant	25 (8.5)	5 (11.1)	20 (8.0)	NS

¹Biliary - Primary sclerosing cholangitis, primary biliary cirrhosis. BMI: Body mass index; NS: Not significant.