Copyright
©The Author(s) 2017.
World J Transplant. Oct 24, 2017; 7(5): 250-259
Published online Oct 24, 2017. doi: 10.5500/wjt.v7.i5.250
Published online Oct 24, 2017. doi: 10.5500/wjt.v7.i5.250
Table 5 Advantages and disadvantages of mobilization strategies
Mobilization strategy | Advantages | Disadvantages |
Growth factor | Cost effective | No anti-myeloma effect |
Successful mobilization in most patients | Multiple injections and collections | |
Predictable schedule | Potential sub-optimal yield | |
CM | Anti-myeloma effect | Cytopenias |
Increased cell yield | Infection risk | |
Fewer apheresis sessions | Hospital admission | |
Potential transfusion requirement | ||
Unpredictable count recovery | ||
Plerixafor | Rapid kinetics | Higher drug cost |
Increased cell yield | ||
Fewer apheresis sessions |
- Citation: Wallis WD, Qazilbash MH. Peripheral blood stem cell mobilization in multiple myeloma: Growth factors or chemotherapy? World J Transplant 2017; 7(5): 250-259
- URL: https://www.wjgnet.com/2220-3230/full/v7/i5/250.htm
- DOI: https://dx.doi.org/10.5500/wjt.v7.i5.250