Lymphocyte recovery is an independent predictor of relapse in allogeneic hematopoietic cell transplantation recipients for acute leukemia

Table 1 Baseline characteristics of patients stratified by lymphocyte recovery n (%)

Variable	ALC > 0.3 (n = 24)	ALC ≤ 0.3 (n = 48)	P value
Patient age in years, median (range)	28 (16-57)	23 (14-63)	0.57
Recipient gender, male	13 (54)	28 (58)	0.74
Diagnosis			0.54
AML	13 (54)	22 (45)
ALL	11 (46)	26 (54)
ECOG	1 (0-2)	0 (0-3)	0.86
Cytogenetics (AML)			0.5
Favorable	3 (25)	2 (10)
Intermediate	7 (58)	15 (71)
High risk	2 (17)	4 (67)
Cytogenetics (ALL)			0.78
Standard	5 (56)	11 (50)
High risk	4 (44)	11 (50)
Female donor/male recipient	4 (17)	11 (23)	0.53
Related donor	21 (88)	42 (88)	1
Status at HCT			0.33
CR1	13 (54)	31 (66)
≥ CR2	11 (46)	16 (34)
ABO Matching			0.89
Match	16 (67)	31 (64)
Major/bidirectional	3 (12)	8 (17)
Minor	5 (21)	9 (19)
TBI containing regimen	8 (33)	30 (63)	0.019
Conditioning intensity			0.19
MAC	18 (75)	42 (88)
RIC	6 (25)	6 (12)

HCT: Hematopoietic stem cell transplant; AML: Acute myeloid leukemia; ALL: Acute lymphoblastic leukemia; ALC: Absolute lymphocyte count; ECOG: Eastern cooperative oncology group; TBI: Total body irradiation; CR: Complete remission; MAC: Myeloablative conditioning; RIC: Reduced intensity conditioning.