Lobar lung transplantation from deceased donors: A systematic review

Table 3 Outcomes of deceased donor lobar lung transplantation compared to conventional lung transplant within the same center

Center	ComparisonGroup with CLTx (number, diagnosis)	PGD (grade)PostOP-ECMO	ICU LOS (d)	Hospital LOS(d)	Survival 1 year	Survival 5 years
Paris	No	Not reported	Not reported	Not reported	ddLLTx: 86%	Not reported
Reina Sofia	Yes (149 - mixed)1	Not reported	Not reported	Not reported	ddLLTx: 50%, CLTx: 72%1	Not reported
Hamburg	Yes (28 - mixed)4	Not reported	Not reported	Not reported	ddLLTx: 85%, CLTx: 72%4	Not reported
Alfred	Yes (329 - mixed)	ddLLTx: 56% ≥ PGD (2)	LLT: 12; CLTx: 4	ddLLTx: 30 CLTx: 21	ddLLTx: 81%, CLTx: 84% (P = 0.115)	ddLLTx: 52%5, CLTx: 37.5%5 (P = 0.115)
Zurich	Yes (219 - mixed)	ddLLTx: 13% PGD (not spec.)	Not reported	Not reported	ddLLTx: 82%; CLTx: 88% (P = 0.56)	ddLLTx: 64%; CLTx: 69% (P = 0.56)
UPMC	Yes (691 - mixed)2, Yes (65 - high LAS)3	ddLLTx: 36% ECMO	Not reported	Not reported	ddLLTx: 76%; CLTx: 83%1; (high LAS): 72%2	Not reported
Foch	Yes (445 - mixed)	ddLLTx: 54% ≥ PGD (1) 20% ECMO	ddLLTx: 17	ddLLTx: 43	ddLLTx: 60%, CLTx: 78% (NS)	ddLLTx: 46%, CLTx: 51% (NS)
Vienna	Yes (778 - mixed)	ddLLTx: 44% ≥ PGD1 32% ECMO	ddLLTx: 17; CLTx: 6	ddLLTx: 33.5 CLTx: 22	ddLLTx: 65.1; CLTx: 84.8% (P < 0.001)	ddLLTx: 54.9% CLTx: 69.9% (P < 0.001)
Leuven	Yes (66 - all CF)	ddLLTx: 25% PGD (3) at 48 h vs CLTx: 9%	ddLLTx: 12 CLTx: 5	ddLLTx: 37 CLTx: 24	ddLLTx: 100%; CLTx: 88.4% (NS)	Not reported

¹From contemporary, but separate reports from same transplant center as the ddLLTx group;

²From contemporary, but separate reports from same transplant center as the ddLLTx group;

³From contemporary, but separate reports from same transplant center as the ddLLTx group;

⁴Provided by center;

⁵Estimated from Kaplan Meier survival curve. PGD: Primary graft dysfunction; ECMO: Extracorporeal membrane oxygenation; ICU: Intensive care unit; LOS: Length of stay; NS: Not statistically significantly different; ddLLTx: Donor lobar lung transplantation; CLTx: Compared to conventional lung transplant.