Cardiovascular disease: Risk factors and applicability of a risk model in a Greek cohort of renal transplant recipients

Table 3 Univariate and multivariate analysis of risk factors for major advance cardiac event in renal transplant recipients

Variables (units of increase)	Univariate		Multivariate
	b (95%CI)	P	b (95%CI)	P
MACE risk (1%)	1.04 (1.02-1.06)	< 0.001
Age (1 yr)	1.05 (1.02-1.10)	0.001	1.05 (1.01-1.08)	0.005
Sex (male reference)	0.45 (0.20-0.99)	0.05	0.58 (0.28-1.37)	0.18
Previous smoker	1.51 (0.73-2.92)	0.21
Current smoker	1.0 (0.44-2.29)	0.99
Systolic BP (1 mmHg)	1.01 (0.99-1.02)	0.61
DM	1.53 (0.78-2.98)	0.21
Previous CVD	3.63 (1.88-7.01)	< 0.001	2.86 (1.45-5.62)	0.006
Number of grafts (first graft reference)	0.50 (0.12-2.02)	0.33
Tοtal time on dialysis and transplantation (1 yr)	0.99 (0.92-1.01)	0.33
Creatinine (1 mg/dL)	0.90 (0.48-1.68)	0.74
Urine protein (1 mg/24 h)	0.99 (0.99-1.00)	0.28
Total cholesterol	0.99 (0.99-1.00)	0.3
(1 mg/dL)
LDL (1 mg/dL)	0.99 (0.98-1.01)	0.46
Hemoglobin (1 g/dL)	1.14 (0.93-1.40)	0.21
PTH (1 pg/mL)	1.00 (0.99-1.00)	0.25
CRP (1 mg/L)	1.01 (0.92-1.09)	0.88

MACE: Major advance cardiac event; BP: Blood pressure; DM: Diabetes mellitus; CVD: Cardiovascular disease; LDL: Low density lipoprotein; PTH: Parathyroid hormone; CRP: C-reactive protein.