Risk factors and outcomes of delayed graft function in renal transplant recipients receiving a steroid sparing immunosuppression protocol

doi:10.5500/wjt.v7.i1.34

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World Journal of Transplantation

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2220-3230

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

World J Transplant. Feb 24, 2017; 7(1): 34-42
Published online Feb 24, 2017. doi: 10.5500/wjt.v7.i1.34

Table 1 Patient demographics

Factor		DGF n = 135 (%)	PGF n = 292 (%)	P value
Recipient age	Years (mean)	51.43 ± 12.19	47.45 ± 13.93	0.0046
Donor age	Years (mean)	51.56 ± 13.05	47.00 ± 15.99	0.0041
Recipient gender	Male	105 (77.8)	178 (61.0)	0.0009
Recipient gender	Female	30 (22.2)	114 (39.0)	0.0009
Donor gender	Male	69 (51.1)	123 (42.1)	0.12
Donor gender	Female	66 (48.9)	167 (57.2)	0.12
Ethnicity	Black	35 (25.9)	41 (14.0)	0.004
Ethnicity	Non-black	100 (74.1)	251 (86.0)	0.004
Time on RRT	Years (mean)	6.37 ± 5.44	5.00 ± 5.07	0.012
Regrafts	1^st	114 (84.4)	261 (89.4)	0.2
Regrafts	> 2^nd	21 (15.6)	31 (10.6)	0.2
Donation type	DCD	45 (33.3)	32 (11.0)	< 0.00001
Donation type	DBD	90 (66.6)	259 (88.7)	< 0.00001
CIT	Hours (mean)	24.70 ± 7.82	21.29 ± 7.58	0.000023
HLA mismatch	Mean	3.47 ± 1.30	3.19 ± 1.58	0.079
Preformed DSA	DSA+	17 (12.6)	18 (6.2)	0.039
Preformed DSA	DSA-	118 (87.4)	274 (93.8)	0.039
Induction	Alemtuzumab	113 (83.7)	292 (84.9)	0.86
Induction	IL2RA	22 (16.3)	44 (15.1)	0.86
Recipient Diabetes	Yes	35 (25.9)	46 (15.8)	0.02
Recipient Diabetes	No	100 (74.1)	246 (84.2)	0.02

CIT: Cold ischaemic time; DGF: Delayed graft function; PGF: Primary graft function; DBD: Brain death; DCD: Circulatory death.

Citation: Willicombe M, Rizzello A, Goodall D, Papalois V, McLean AG, Taube D. Risk factors and outcomes of delayed graft function in renal transplant recipients receiving a steroid sparing immunosuppression protocol. World J Transplant 2017; 7(1): 34-42
URL: https://www.wjgnet.com/2220-3230/full/v7/i1/34.htm
DOI: https://dx.doi.org/10.5500/wjt.v7.i1.34