Time spent in hospital after liver transplantation: Effects of primary liver disease and comorbidity

Table 4 Sensitivity analysis of the multivariable linear regression for transplant length of stay including patients who died within the first two years after liver transplantation (4490 patients)

Variable	Coefficient for TLOS
	(d)	95%CI	P-value
Primary liver disease groups1
Cancer	0.0	Reference	0.001
Acute hepatic failure	3.7	0.2, 7.2
Hepatitis C cirrhosis	3.3	0.6, 6.1
Primary sclerosing cholangitis	-0.3	-3.2, 2.7
Hepatitis B cirrhosis	0.6	-4.0, 5.2
Primary biliary cirrhosis	-1.5	-4.4, 1.4
Alcoholic cirrhosis	1.1	-1.3, 3.5
Autoimmune and cryptogenic	0.5	-2.5, 3.4
Metabolic liver disease	3.3	-0.9, 7.6
Other liver disease	5.9	2.5, 9.2
Comorbidities2
Cardiovascular disease	8.7	5.8, 11.5	< 0.001
Congestive cardiac failure	7.7	3.6, 11.8	< 0.001
Connective tissue disease	-0.3	-4.0, 3.3	0.86
Dementia	1.1	-2.4, 4.6	0.54
Diabetes mellitus	1.1	-0.6, 2.8	0.21
Non-hepatic malignancy	0.9	-4.6, 6.3	0.76
Chronic pulmonary disease	1.2	-1.1, 3.5	0.3
Chronic renal disease	1.7	-1.0, 4.4	0.22

¹A coefficient for primary liver disease groups represents a difference in days between LOS in the primary liver disease group and the reference group (cancer);

²A coefficient for comorbidities represents a difference in days between LOS of patients with and without the comorbidity. The multivariable model was adjusted for primary liver disease group, comorbidities, recipient age, sex, log bilirubin, log creatinine, INR, sodium, transplant centre and time period of transplantation. TLOS: Transplant length of stay; INR: International normalised ratio.