Review
Copyright ©The Author(s) 2016.
World J Transplant. Dec 24, 2016; 6(4): 632-645
Published online Dec 24, 2016. doi: 10.5500/wjt.v6.i4.632
Table 3 Overview of mutations in complement factor H related protein genes
Genetic defectPhenotypical expression
Duplication in the CFHR5 geneC3 glomerulopathy (CFHR5 nephropathy)
Duplication in the CFHR1 geneC3 glomerulopathy
Hybrid CFHR3/CFHR1 geneC3 glomerulopathy
Hybrid CFHR2/CFHR5 geneC3 glomerulopathy
Hybrid CFH/CFHR1 geneaHUS
Hybrid CFH/CFHR3 geneaHUS